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ABClone very large DNA fragment cloning platform


ACIES BIO developed a highly efficient one-step in vivo recombinational cloning technology platform ABCloneTM to enable:

  • fast and efficient cloning of long (200kb+) and complex natural DNA fragments
  • site-specific introduction of virtually any genetic modification
  • assembly of completely synthetic or semi-synthetic DNA fragments

ABCloneTM has been extensively proven for efficient and rapid cloning of large and complex high-GC and repetitive DNA regions, such as numerous biosynthetic gene clusters from Actinomycetes, as well as mammalian immunoglobulin genes. ACIES BIO provides ABCloneTM as a stand alone service for getting quickly your long DNA fragment sub-cloned into plasmid vector of your choice, or use it in combination with other ACIES BIO services built on years of experience of our scientists in natural compound production by microbial fermentations.



Acies was part of Bio World 2017, a unique forum for industry global leaders, policy makers and investors.  
The action is co-financed by the Republic of Slovenia and European Union from European Regional Development Fund.

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Within public call "Enhancing innovation potential and competences in companies", Acies Bio was recognised as one of the innovative companies with best potential to contribute to international competitiveness of Slovenia through smart specialisation.


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