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ABClone very large DNA fragment cloning platform


ACIES BIO developed a highly efficient one-step in vivo recombinational cloning technology platform ABCloneTM to enable:

  • fast and efficient cloning of long (200kb+) and complex natural DNA fragments
  • site-specific introduction of virtually any genetic modification
  • assembly of completely synthetic or semi-synthetic DNA fragments

ABCloneTM has been extensively proven for efficient and rapid cloning of large and complex high-GC and repetitive DNA regions, such as numerous biosynthetic gene clusters from Actinomycetes, as well as mammalian immunoglobulin genes. ACIES BIO provides ABCloneTM as a stand alone service for getting quickly your long DNA fragment sub-cloned into plasmid vector of your choice, or use it in combination with other ACIES BIO services built on years of experience of our scientists in natural compound production by microbial fermentations.



European Medicines Agency (EMA) granted orphan medicinal product designation to its lead compound CAB1803 for Pantothenate-kinase-associated neurodegeneration (PKAN)

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Acies Bio received the “Jesenko Award” from Biotechnical Faculty of University of Ljubljana. The award recognizes institutions for their outstanding research work in the field of biotechnology.

Scientists at ACIES BIO made a breakthrough innovation: high-value technology that uses unique and economic bioprocess to convert acid waste whey from dairy factories into high value animal feed products (vitamin B12) and clean water in the same process. Check out Whey2Value!



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Within H2020 SME Innovation Associate project we invite a “Disease Model Development Manager” to join our team.




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ABCloneTM is fast and efficient solution for cloning of large natural and synthetic DNA fragments. We provide ABCloneTM as a stand alone service for getting quickly your long DNA fragment sub-cloned into plasmid vector of your choice.

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